Regenerative potential of multinucleated cells: bone marrow adiponectin-positive multinucleated cells take the lead.

Shiva MoeinNaser AhmadbeigiRezvan AdibiSara KamaliKobra MoradzadehPardis NematollahiNance Beyer NardiYousof Gheisari

Published in: Stem cell research & therapy (2023)

A population of resistant multinucleated cells reside in the BM that serves as the common origin of stromal and hematopoietic lineages with a key role in tissue regeneration. Furthermore, this study underscores the contribution of adipocytes in BM reconstruction.

Keyphrases

bone marrow
induced apoptosis
cell cycle arrest
stem cells
mesenchymal stem cells
metabolic syndrome
type diabetes
oxidative stress
climate change