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Prophylactic Negative-pressure Wound Therapy Prevents Surgical Site Infection in Abdominal Surgery: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials and Observational Studies.

Jérémy MeyerElin RoosZiad AbbassiNicolas C BuchsFrédéric RisChristian Toso
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Existing studies suggest that pNPWT on closed wounds is protective against the occurrence of SSI in abdominal surgery, but these findings need to be confirmed by more high-quality evidence, preferentially in subgroups of patients with an incidence of SSI ≥20% in the control arm.
Keyphrases
  • surgical site infection
  • risk assessment
  • risk factors
  • case control
  • mouse model
  • stem cells
  • wound healing