Does progesterone administration in preterm labor influence Treg cells?

Ana Luísa Fialho de Amaral AreiaSofia Vale-PereiraAna Vaz-AmbrósioVera AlvesPaulo Rodrigues-SantosManuel Santos RosaPaulo MouraAnabela Mota-Pinto

Published in: Journal of perinatal medicine (2017)

This research demonstrated a considerable increase in the Treg cell pool after progesterone treatment. This indicates a possible mechanism for progesterone treatment benefits in preterm labor, potentially increasing its more rational use.

Keyphrases

preterm birth
stem cells
single cell
gestational age
cell therapy
combination therapy
signaling pathway
cell proliferation
mesenchymal stem cells
cell cycle arrest
bone marrow
replacement therapy
endoplasmic reticulum stress