Analysis of nonsynonymous SNPs in candidate genes that influence bovine temperament and evaluation of their effect in Brahman cattle.
Gilberto Ruiz-De-La-CruzAna María Sifuentes RincónFrancisco Alejandro Paredes-SánchezGaspar Manuel Parra-BracamonteEduardo CasasDavid G RileyGeorge Allen PerryThomas H WelshRonald D RandelPublished in: Molecular biology reports (2024)
The results showed that in silico analysis could direct the selection of nsSNPs with the potential to change the protein. Non-synonymous single nucleotide polymorphisms causing structural changes and reduced protein stability were identified. Only rs209984404-HTR1B shows that the allele affecting protein stability was associated with the genotype linked to docility in cattle.