Transcriptomic Analysis of Laser Capture Microdissected Tumors Reveals Cancer- and Stromal-Specific Molecular Subtypes of Pancreatic Ductal Adenocarcinoma.

David J BirnbaumSebastian K S Begg Pascal Finetti Charles R VanderburgAnupriya S KulkarniAzfar NeyazThomas HankEric TaiVikram DeshpandeFrançois BertucciDaniel BirnbaumKeith D LillemoeAndrew L Warshaw Mari A Mino-KenudsonCarlos Fernandez-Del CastilloDavid Tsai TingAndrew S Liss

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Our results identified specific signatures from the epithelial and the stroma components of PDAC, which add clarity to the nature of PDAC molecular subtypes and may help predict survival.

Keyphrases

papillary thyroid
bone marrow
single molecule
squamous cell
genome wide
gene expression
dna methylation
high resolution
childhood cancer