Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway.
Zheng-Kun ZhangYan ZhouJun CaoDan-Yang LiuLi-Hong WanPublished in: The Journal of pharmacy and pharmacology (2021)
These findings indicated that RA could be beneficial to septic-associated lung injury through anti-apoptosis effect.
Keyphrases
- endoplasmic reticulum stress
- induced apoptosis
- acute kidney injury
- cell death
- rheumatoid arthritis
- cardiovascular events
- oxidative stress
- signaling pathway
- high fat diet induced
- mouse model
- risk factors
- disease activity
- type diabetes
- cardiovascular disease
- ankylosing spondylitis
- adipose tissue
- insulin resistance
- interstitial lung disease
- cell surface