Increased plasma lipopolysaccharide-binding protein and altered inflammatory mediators in overweight women suggest a state of subclinical endotoxemia.
Christine N MetzXiangying XueProdyot K ChatterjeeRobert AdelsonMichael BrinesKevin J TraceyPeter K GregersenValentin A PavlovPublished in: bioRxiv : the preprint server for biology (2023)
These results document the presence of a pro-inflammatory state in overweight compared with lean women and are of interest for further evaluation of evidence of inflammation in overweight individuals as an additional risk factor for cardiometabolic disease.
Keyphrases
- weight loss
- polycystic ovary syndrome
- physical activity
- weight gain
- binding protein
- oxidative stress
- pregnancy outcomes
- lps induced
- toll like receptor
- cervical cancer screening
- inflammatory response
- type diabetes
- breast cancer risk
- pregnant women
- skeletal muscle
- bone mineral density
- immune response
- postmenopausal women