RGS4 Regulates Proliferation And Apoptosis Of NSCLC Cells Via microRNA-16 And Brain-Derived Neurotrophic Factor.
Zheng HeLianhua YuShiyi LuoQi LiShuhong HuangYunhe AnPublished in: OncoTargets and therapy (2019)
This study revealed that RGS4 overexpression positively correlated with the development of NSCLC. TDownstream RGS4 targets (eg, miR-16 and BDNF) might be involved in the development of NSCLC and may serve as potential therapeutic targets for its treatment.
Keyphrases
- small cell lung cancer
- cell cycle arrest
- advanced non small cell lung cancer
- cell proliferation
- induced apoptosis
- cell death
- endoplasmic reticulum stress
- long non coding rna
- oxidative stress
- signaling pathway
- brain metastases
- pi k akt
- transcription factor
- long noncoding rna
- stress induced
- smoking cessation
- replacement therapy