CircWAC induces chemotherapeutic resistance in triple-negative breast cancer by targeting miR-142, upregulating WWP1 and activating the PI3K/AKT pathway.
Lei WangYehui ZhouLiang JiangLinlin LuTiantian DaiAoshuang LiYan ChenLifeng ZhangPublished in: Molecular cancer (2021)
CircWAC/miR-142/WWP1 form a competing endogenous RNA (ceRNA) network to regulate PI3K/AKT signaling activity in TNBC cells and affect the chemosensitivity of cells.