RelB upregulates PD-L1 and exacerbates prostate cancer immune evasion.
Yanyan ZhangShuyi ZhuYuanyuan DuFan XuWenbo SunZhi XuXiumei WangPeipei QianQin ZhangJifeng FengYong XuPublished in: Journal of experimental & clinical cancer research : CR (2022)
This study deciphers the molecular mechanism by which tumourous RelB contributes to immune evasion by inhibiting T cell immunity via the amplification of the PD-L1/PD-1-mediated immune checkpoint.