Risk Factors and Clinicopathological Features for Developing a Subsequent Primary Cutaneous Squamous and Basal Cell Carcinomas.
Magdalena CiążyńskaMarta PabianekMartyna SławińskaAdam ReichBogumił LewandowskiKatarzyna SzczepaniakMałgorzata UłańskaDariusz NejcRobert BrodowskiMichał SobjanekWitold OwczarekGrażyna Kamińska-WinciorekDariusz LangeMonika SłowińskaKatarzyna WróbelAndrzej BieniekAnna WoźniackaAnika PękalaŁukasz KuncmanMagdalena SalińskaMarcin NowetaMałgorzata SkibińskaJoanna NarbuttKarol CiążyńskiMarta LewandowskaElżbieta Dziankowska-ZaborszczykAleksandra LesiakPublished in: Cancers (2022)
The most crucial risk factors for developing subsequent KC are being of a male gender, an aggressive tumor subtype, and previous history of multiple skin cancers. Basal cell carcinoma subtypes, such as infiltrative basosquamous, with aggressive growth patterns predispose not only to increased risk for the recurrence but are also expected to be at higher risk of subsequent KCs.