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Changes in brain function during negative emotion processing in the long-term course of depression.

Verena EnnekingMelissa KlugTiana BorgersKatharina DohmDominik GrotegerdLisa Marie FrankenbergerCarina HülsmannHannah LemkeSusanne MeinertElisabeth J LeehrNils OpelJanik GoltermannMaike RichterLena WaltemateJoscha BöhnleinLisa SindermannJonathan ReppleJochen BauerMareike ThomasUdo DannlowskiRonny Redlich
Published in: The British journal of psychiatry : the journal of mental science (2022)
This study reveals course of illness-associated activity changes in emotion processing areas. Patients in full remission show a normalisation of their baseline hypo-responsiveness to the activation level of healthy controls after 2 years. Brain function during emotion processing could further serve as a potential predictive marker for future relapse.
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