Fracture definitions in observational osteoporosis drug effects studies that leverage healthcare administrative (claims) data: a scoping review.

Natalia KonstantelosA M RzepkaA M BurdenA M CheungS KimP GrootendorstS M Cadarette

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2022)

There is ambiguity and heterogeneity in fracture outcome definitions in studies that leverage claims data. Better transparency in outcome reporting is needed. Future exploration of how fracture definitions impact study results is warranted.

Keyphrases

healthcare
health insurance
electronic health record
hip fracture
big data
adverse drug
case control
postmenopausal women
bone mineral density
single cell
current status
emergency department
machine learning
deep learning