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A Physiology-Based Mathematical Model to Understand Drug Delivery from Contact Lenses to the Back of the Eye.

Nadia ToffolettoBenilde SaramagoAna Paula SerroAnuj Chauhan
Published in: Pharmaceutical research (2023)
The model constitutes a first step towards the possibility of predicting the ocular drug distribution and the treatment efficacy in the early stage of contact lens development, and it may help reduce both the need for in vivo tests (with ethical and economic advantages) and the gap between the lens design and clinical application. It also allows for an improved understanding of drug transport in the eye.
Keyphrases
  • early stage
  • drug delivery
  • cataract surgery
  • adverse drug
  • cancer therapy
  • emergency department
  • radiation therapy
  • sentinel lymph node
  • smoking cessation