Incidence, predictive factors and severity of methotrexate-related liver injury in rheumatoid arthritis: a longitudinal cohort study.

Shunsuke MoriNobuyuki ArimaMasahiro ItoYukitaka UekiYasuyo AbeKiyoshi AoyagiShigetoshi Fujiyama

Published in: Rheumatology advances in practice (2020)

Aggravation of underlying fatty liver to NASH with fibrosis seems to be an important mechanism of liver injury that occurs in MTX-treated RA patients.

Keyphrases

liver injury
drug induced
rheumatoid arthritis
end stage renal disease
newly diagnosed
ejection fraction
disease activity
chronic kidney disease
risk factors
prognostic factors
peritoneal dialysis
high dose
systemic sclerosis