Herpesviridae lung reactivation and infection in patients with severe COVID-19 or influenza virus pneumonia: a comparative study.
Charles-Edouard LuytSonia BurrelDavid MokraniMarc Pineton de ChambrunDomitille LuytJuliette ChommelouxVincent GuiraudNicolas BréchotMatthieu SchmidtGuillaume HekimianAlain CombesDavid BoutolleauPublished in: Annals of intensive care (2022)
HSV and CMV lung reactivations are frequent in COVID-19 patients, but not more frequent than in patients with influenza-associated severe pneumonia, despite a higher severity of illness at intensive care unit admission of the latter and a longer duration of mechanical ventilation of the former. Although no impact on outcome of HSV and CMV lung reactivations was detected, the effect of antiviral treatment against these Herpesviridae remains to be determined in these patients.
Keyphrases
- mechanical ventilation
- intensive care unit
- sars cov
- respiratory failure
- end stage renal disease
- acute respiratory distress syndrome
- coronavirus disease
- newly diagnosed
- ejection fraction
- emergency department
- chronic kidney disease
- early onset
- prognostic factors
- herpes simplex virus
- peritoneal dialysis
- drug induced
- respiratory syndrome coronavirus