Systemic antibiotic therapy as an adjunct to non-surgical peri-implantitis treatment: A single-blind RCT.
Yvonne Catharina Maria de WaalTine E VangstedArie Jan Van WinkelhoffPublished in: Journal of clinical periodontology (2021)
Systemic antibiotic therapy of AMX/MTZ does not improve clinical and microbiological outcomes of non-surgical peri-implantitis treatment and should not be routinely recommended. Although complete disease resolution may be difficult to achieve, meticulously performed full-mouth non-surgical treatment, achieving a high level of daily oral hygiene and healthy periodontal tissues, can significantly improve the starting position of the subsequent (surgical) peri-implantitis treatment phase.