Administration of Aripiprazole Alleviates Memory Impairment and Restores Damaged Glutamatergic System in 5xFAD Mice.
Hae-June LeeHyun-Yong KimSe Jong OhYeonghoon SonKyung Jun KangKyung Rok NamJae Yong ChoiPublished in: Molecular imaging and biology (2024)
The administration of aripiprazole alleviated memory impairment and restored the damaged glutamatergic system in 5xFAD mice. Although the use of aripiprazole in AD patients may be a constraint in terms of safety, we confirmed the possibility that the administration of antipsychotic drugs can be effective in AD.