Antiviral CD8 + T cell immune responses are impaired by cigarette smoke and in COPD.
Jie ChenXinyuan WangAdrian SchmalenSophia HainesMartin WolffHuan MaHuabin ZhangMircea Gabriel StoleriuJohannes NowakMisako NakayamaMarta BuenoJudith BrandsAna L MoraJanet S LeeSusanne Krauss-EtschmannAnna DmitrievaMarion FrankenbergerThomas P HoferElfriede NoessnerAndreas MoosmannJürgen BehrKatrin MilgerCornelia A DeegClaudia A Staab-WeijnitzStefanie M HauckHeiko AdlerTorsten GoldmannKaroline I GaedeJochen BehrendsIlona E KammerlSilke MeinersPublished in: The European respiratory journal (2023)
T cells upon virus infection. This adds important mechanistic insight on how cigarette smoke mediates increased susceptibility of smokers and COPD patients to viral infections.