Microstructural and Metabolic Changes in Normal Aging Human Brain Studied with Combined Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging.

Nima MahmoudiM DadakP Bronzlik Andrew A MaudsleyS SheriffHeinrich Lanfermann Xiao-Qi Ding

Published in: Clinical neuroradiology (2023)

Normal aging in human brain is associated with coexistent brain regional metabolic alterations and microstructural changes, which may be related to age-related decline in cognitive, affective and psychomotor domains of life in the older population.

Keyphrases

white matter
high resolution
resting state
multiple sclerosis
contrast enhanced
functional connectivity
molecular docking
cerebral ischemia
magnetic resonance
computed tomography
middle aged
mass spectrometry
brain injury
fluorescence imaging
molecular dynamics simulations