Emergence of highly profibrotic and proinflammatory Lrat + Fbln2 + HSC subpopulation in alcoholic hepatitis.

Steven BalogReika FujiwaraStephanie Q PanKhairat B El-BaradieHye Yeon ChoiSonal SinhaQihong YangKinji AsahinaYibu ChenMeng LiMatthew SalomonStanley W-K NgHidekazu Tsukamoto

Published in: Hepatology (Baltimore, Md.) (2022)

A highly profibrotic, inflammatory, and immunoregulatory Lrat+Fbln2+ subpopulation emerges from HSCs in AH and may contribute to the inflammatory and immunoreactive nature of AH.

Keyphrases

oxidative stress
liver injury