Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination.

Patrick R DoranNatalie Fomin-ThunemannRockwell P TangDora BalogBernhard ZimmermanKıvılcım KılıçEmily A MartinSreekanth KuraHarrison P FisherGrace ChabbottJoel HerbertBradley C RauscherJohn X JiangSava SakadzicDavid A Boas Anna Devor Ichun Anderson Chen Martin Thunemann

Published in: Neurophotonics (2024)

Our widefield microscope design with a single camera can be used to acquire multiple aspects of brain physiology and is compatible with behavioral readouts of pupil diameter.

Keyphrases

high resolution
white matter
resting state
single molecule
optic nerve
high speed
convolutional neural network
energy transfer
cerebral ischemia
multiple sclerosis
computed tomography
image quality
machine learning
magnetic resonance
blood brain barrier
brain injury
deep learning
quantum dots