Incidence of dementia and Alzheimer's Disease, genetic susceptibility and grip strength among older adults.

Youngwon Kim Mengyao WangStephen J SharpShiu Lun Au YeungShan LuoHaeyoon JangZhu Liduzi JiesisibiekeQiaoxin ShiZiyuan ChenSoren Brage

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)

Older adults with higher PRS for ADD are at higher risk of developing dementia and AD. Risk of dementia and AD was lower in individuals with higher grip strength, regardless of their level of genetic susceptibility to ADD.

Keyphrases

mild cognitive impairment
cognitive impairment
cognitive decline
genome wide
risk factors
copy number
gene expression
middle aged
dna methylation