Acute systemic inflammatory response to lipopolysaccharide stimulation in pigs divergently selected for residual feed intake.
Haibo LiuKristina M FeyeYet T NguyenAnoosh RakhshandehCrystal L LovingJack C M DekkersNicholas K GablerChristopher K TugglePublished in: BMC genomics (2019)
The pig lines divergently selected for RFI had a largely similar response to LPS stimulation. However, the low-RFI line had a relatively lower-level, but longer-lasting, inflammatory response compared to the high-RFI line. Our results suggest selection for feed efficient pigs does not significantly compromise a pig's acute systemic inflammatory response to LPS, although slight differences in intensity and duration may occur.