Suprachoroidal spheroidal mesenchymal stem cell implantation in retinitis pigmentosa: clinical results of 6 months follow-up.

Berna Özkan Busra Yilmaz Tugan Cansu Hemşinlioğlu Gözde Sır Karakuş Özlem Şahin Ercüment Ovalı

Published in: Stem cell research & therapy (2023)

Suprachoroidal implantation of MSCs in the form of spheroids as a stem cell therapy for RP patients with relatively good visual acuity has an improving effect on BCVA, VF and mfERG recordings during the 6-month follow-up period. Spheroidal MSCs with enhanced effects may be more successful in preventing apoptosis and improving retinal tissue healing in RP patients.

Keyphrases

mesenchymal stem cells
stem cells
end stage renal disease
umbilical cord
ejection fraction
oxidative stress
chronic kidney disease
prognostic factors
peritoneal dialysis
bone marrow
endoplasmic reticulum stress
cell therapy
diabetic retinopathy
patient reported outcomes
cell proliferation
pi k akt