Association between sagittal alignment and loads at the adjacent segment in the fused spine: a combined clinical and musculoskeletal modeling study of 205 patients with adult spinal deformity.
Dominika IgnasiakPascal BehmAnne F MannionFabio GalbuseraFrank KleinstückTamás F FeketeDaniel HaschtmannDezsö JeszenszkyLaura ZimmermannSarah Richner-WunderlinAlba Vila-CasademuntFerran PelliséIbrahim ObeidJavier PizonesFrancisco J Sánchez Pérez-GruesoMuhammed Ilkay KaramanAhmet AlanayÇaglar YilgorStephen J FergusonMarkus Loiblnull nullPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2022)
Spinal loads were estimated for patient-specific full spinal alignment profiles in a large cohort of patients with ASD pre-and postoperatively. Loads on the proximal segments were greater in association with sagittal malalignment and malorientation of proximal vertebra. Future work should explore whether they provide a causative mechanism explaining the associated risk of proximal junction complications.