[HLA alleles heterogeneity in a sample of colombian patients with a diagnosis of psoriatic arthritis].
María Alejandra Meneses-ToroÓmar Javier CalixtoPaula Andrea Chacón-JaramilloMónica Acevedo-GodoyLuisa Constanza Robayo-BeltránCamilo Vera-ParraJuan Manuel Bello-GualteroWilson Bautista-MolanoVerónica Noguera-CastroConsuelo Romero-SánchezPublished in: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) (2024)
Curiously, there were no positive results for HLAB*27, which may be related to the population mix. HLA Cw6 is traditionally associated with psoriasis. However, its absence has been linked to nail disorders and PsA; consequently, in our study, it had a low frequency (2,2%). On the other hand, HLA*B1302 has been related to the disease and its early onset; in the healthy Colombian population, it has been described in 0,92%; in our group, it is found to be significant in patients without establishing a clinical association. Few previous studies report HLA results in PsA in Colombia.