Testosterone replacement therapy of opioid-induced male hypogonadism improved body composition but not pain perception: a double-blind, randomized, and placebo-controlled trial.
Dorte GlintborgHenrik Bjarke VaegterLouise Lehmann ChristensenEmma BendixThomas Graven-NielsenPer Grünwald AndersenMarianne AndersenPublished in: European journal of endocrinology (2020)
Six months of TRT improved body composition in men with opioid-induced hypogonadism without significant changes in outcomes of pain perception, quality of life, or adrenal function.
Keyphrases
- body composition
- replacement therapy
- chronic pain
- pain management
- resistance training
- smoking cessation
- bone mineral density
- double blind
- high glucose
- diabetic rats
- neuropathic pain
- drug induced
- open label
- oxidative stress
- clinical trial
- skeletal muscle
- spinal cord injury
- spinal cord
- phase iii
- adipose tissue
- middle aged