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Ru(II)-Catalyzed and acidity-controlled tunable [5+1]/[5+2] annulation for building ring-fused quinazolines and 1,3-benzodiazepines.

Yurong YangKaixin ZhangJian YangGuoxun ZhuWeijie ChenChao ZhangZhi ZhouWei Yi
Published in: Chemical communications (Cambridge, England) (2020)
The Ru(ii)-catalyzed tunable [5+1]/[5+2] annulation of N-benzo[d]imidazole indolines with propargyl carbonates has been realized for the divergent synthesis of ring-fused quinazolines and 1,3-benzodiazepines bearing various functional groups. These transformations represent an efficient and practical strategy in constructing complex heterocycles via diversified C-H functionalization. A distinctive acidity-controlled reaction manner has been clarified to account for the chemoselectivity.
Keyphrases
  • energy transfer
  • room temperature
  • quantum dots
  • light emitting