Proton pump inhibitors increase risk of bone fractures in men with cirrhosis: a population-based study.

Christian LabenzMarcus-Alexander WörnsCharles C AdarkwahPeter R GalleJörn Markus SchattenbergKarel Kostev

Published in: Alimentary pharmacology & therapeutics (2020)

PPI use was associated with bone fractures in a dose-dependent fashion in patients with cirrhosis. PPI use in these patients should be based on a careful risk-benefit assessment.

Keyphrases

end stage renal disease
bone mineral density
ejection fraction
chronic kidney disease
newly diagnosed
protein protein
prognostic factors
soft tissue
bone loss
patient reported outcomes
middle aged
postmenopausal women
patient reported