Prevalence and genetic variability of occult hepatitis B virus in a human immunodeficiency virus positive patient cohort in Gondar, Ethiopia.
Nishi H PatelVanessa Meier-StephensonMeaza GenetuDebasu DamtieEbba AbateShitaye AlemuYetework AlekaGuido Van MarleKevin FonsecaCarla S CoffinTekalign DeressaPublished in: PloS one (2020)
This study found a high rate of occult hepatitis B in HIV patients. Further, high rates of mutations associated with HBV reactivation, drug resistance, and HCC risk were detected in these patients. These data highlighted the need for integrating OHB screening for proper management of liver diseases in HIV patients.
Keyphrases
- human immunodeficiency virus
- hepatitis b virus
- end stage renal disease
- antiretroviral therapy
- ejection fraction
- chronic kidney disease
- hepatitis c virus
- newly diagnosed
- hiv infected
- peritoneal dialysis
- hiv positive
- risk factors
- electronic health record
- hiv testing
- genome wide
- case report
- liver failure
- patient reported