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Mendelian randomization of circulating proteome identifies IFN-γ as a druggable target in aplastic anemia.

Shanshan QinYingxin JiangYang OuYanxia ZhanLili JiPengcheng XuXia ShaoHao ChenTong ChenYunfeng Cheng
Published in: Annals of hematology (2024)
High levels of circulating IFN-γ levels might increase the risk of AA and might provide a potential novel target for AA.
Keyphrases
  • dendritic cells
  • immune response
  • chronic kidney disease
  • genome wide
  • allogeneic hematopoietic stem cell transplantation
  • iron deficiency
  • gene expression
  • risk assessment