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Immuno-genomic characterisation of high-grade serous ovarian cancer reveals immune evasion mechanisms and identifies an immunological subtype with a favourable prognosis and improved therapeutic efficacy.

Jie SunCongcong YanDandan XuZicheng ZhangKe LiXiaobo LiMeng ZhouDapeng Hao
Published in: British journal of cancer (2022)
Our study characterised the immunogenomic landscape and refined the immunological classifications of HGSOC. This may improve the selection of patients with HGSOC who are suitable candidates for immunotherapy.
Keyphrases
  • high grade
  • low grade
  • genome wide
  • copy number