Netrin-1 and multiple sclerosis: a new biomarker for neuroinflammation?

Patricia MuleroC CórdovaM HernándezR MartínB GutiérrezJ C MuñozN RedondoI GallardoN TéllezMaria Luisa Nieto

Published in: European journal of neurology (2017)

Netrin-1 decreased in EAE and in MS patients, mainly during relapse, suggesting an anti-inflammatory role of netrin-1. Further research should be performed in a larger cohort of patients to validate netrin-1 as a biomarker of MS inflammatory activity.

Keyphrases

multiple sclerosis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
mass spectrometry
peritoneal dialysis
prognostic factors
anti inflammatory
traumatic brain injury
ms ms
inflammatory response
lipopolysaccharide induced
brain injury
blood brain barrier
free survival