Total flavones of Rhododendron simsii Planch flower protect rat hippocampal neuron from hypoxia-reoxygenation injury via activation of BKCa channel.

Yan GuoXiao-Meng YuShuo ChenJi-Yue Wen Zhi-Wu Chen

Published in: The Journal of pharmacy and pharmacology (2019)

Total flavones of R. simsii Planch flower had a protective effect against H/R injury in rat hippocampal neuron, and activation of BKCa channel may contribute to the neuroprotection.

Keyphrases

cerebral ischemia
oxidative stress
brain injury
endothelial cells
subarachnoid hemorrhage