Stille vs. Suzuki - cross-coupling for the functionalization of diazocines.
Melanie WaltherWaldemar KipkeRaul RenkenAnne StaubitzPublished in: RSC advances (2023)
Diazocines are azobenzene derived macrocyclic photoswitches with well resolved photostationary states for the ( E )- and ( Z )-isomers, which improves their addressability by light. In this work, effective procedures for the stannylation and borylation of diazocines in different positions are reported. Their use in Stille cross-coupling and Suzuki cross-coupling reactions with organic bromides is demonstrated in yields of 47-94% (Stille cross-coupling) and 0-95% (Suzuki cross-coupling), respectively.
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