Influence of fibroids on cell-free DNA screening accuracy.

Fergus P ScottM MenezesM E SmetK CareyT HardyT FullstonD L RolnikA McLennan

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)

Most women with fibroids do not have an abnormal result on genome-wide cfDNA screening. However, CNVs due to fibroids are associated with false positive SAs, but do not appear to influence cfDNA screening accuracy for the common autosomal trisomies or sex chromosome abnormalities. This article is protected by copyright. All rights reserved.

Keyphrases

genome wide
dna methylation
pregnancy outcomes
gene expression
pregnant women