Login / Signup

Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease.

Anna H BoerwinkleJulie K WischCharles D ChenBrian A GordonOmar H ButtSuzanne E SchindlerCourtney SutphenShaney FloresAylin DincerTammie L S BenzingerAnne M FaganJohn C MorrisBeau M Ances
Published in: Neurology (2021)
CSF Aβ42 and PiB PET best agree when acquired in close temporal proximity, whereas CSF phosphorylated tau precedes flortaucipir PET by 4 to 8 years. CSF and neuroimaging measures of neurodegeneration have low correspondence and are not interchangeable at any time interval.
Keyphrases
  • cerebrospinal fluid
  • pet imaging
  • pet ct
  • positron emission tomography
  • computed tomography
  • mild cognitive impairment