Personalized brain MRI revealed distinct functional and anatomical disruptions in Creutzfeldt-Jakob disease and Alzheimer's disease.

Yanjun GuoJianxun RenWeigang CuiLouisa DahmaniDanhong WangXiaoxuan FuMeiling LiShiyi LiYi ZhangXue LinZhen ZhenYichen XuDan XieHongzhi GuanFang YiJiawei WangQi ShiHesheng Liu

Published in: CNS neuroscience & therapeutics (2023)

CJD shows unique anatomical and functional disruptions in the cerebral cortex, distinct from AD. Rapid progression of CJD affects both the cortical thickness and rsFC in the association cortex.

Keyphrases

functional connectivity
resting state
magnetic resonance imaging
cerebral ischemia
white matter
computed tomography
optical coherence tomography
cognitive decline
multiple sclerosis
cone beam computed tomography