Combinational approach of retrospective clinical evidence and transcriptomics highlight AMH superiority to FSH, as successful ICSI outcome predictor.

Stavroula Lila KastoraOlga TriantafyllidouGeorgios KolovosAthanasios KastorasGeorgios SigalosNikos Vlahos

Published in: Journal of assisted reproduction and genetics (2020)

Overall, this study offers new insight on AMH effects upon cumulus cells and new aspects on how AMH might promote oocyte integrity and embryo viability at a biochemical level as well as add to the current body of evidence supporting AMH clinical potential as a more sensitive marker of IVF outcomes in comparison with FSH, regarding numbers of oocytes received and high-quality day 2 and day 3 embryos.

Keyphrases

induced apoptosis
pregnancy outcomes
single cell
type diabetes
oxidative stress
signaling pathway
metabolic syndrome
insulin resistance
climate change