Efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute pain after orthopedic trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma and the Orthopedic Trauma Association.
Patrick B MurphyGeorge KasotakisElliott R HautAnna MillerEdward HarveyEric HasenboehlerThomas HigginsJoseph HoeglerHassan MirSarah CantrellWilliam T ObremskeyMeghan WallyBasem AttumRachel SeymourNimitt PatelWilliam RicciJennifer J FreemanKrista L HainesBrian K YorkgitisBrandy B Padilla-JonesPublished in: Trauma surgery & acute care open (2023)
In patients with traumatic fractures, NSAIDs appear to reduce post-trauma pain, reduce the need for opioids and have a small effect on non-union. We conditionally recommend the use of NSAIDs in patients suffering from traumatic fractures as the benefit appears to outweigh the small potential risks.
Keyphrases
- anti inflammatory drugs
- chronic pain
- pain management
- trauma patients
- spinal cord injury
- end stage renal disease
- ejection fraction
- neuropathic pain
- newly diagnosed
- chronic kidney disease
- primary care
- prognostic factors
- liver failure
- south africa
- spinal cord
- intensive care unit
- atrial fibrillation
- patient reported outcomes
- acute respiratory distress syndrome
- aortic dissection