Unbiased estimates of cerebrospinal fluid β-amyloid 1-42 cutoffs in a large memory clinic population.

Daniela BertensBetty M TijmsPhilip ScheltensCharlotte E TeunissenPieter Jelle Visser

Published in: Alzheimer's research & therapy (2017)

Mixture modeling is a robust method to determine cutoffs for CSF β-amyloid 1-42. It might better capture biological changes that are related to AD than cutoffs based on clinical diagnosis.

Keyphrases

cerebrospinal fluid
primary care
working memory