Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia.
Jeffrey L CarsonMaria Mori BrooksPaul C HébertShaun G GoodmanMarnie BertoletSimone A GlynnBernard R ChaitmanTabassome SimonRenato D LopesAndrew M GoldsweigAndrew P DeFilippisJ Dawn AbbottBrian J PotterFrançois-Martin CarrierSunil V RaoHoward A CooperShahab GhafghaziDean A FergussonWilliam J KostisHelaine NoveckSarang KimMeechai TessaleeGregory DucrocqPedro Gabriel Melo de Barros E SilvaDarrell J TriulziCaroline AlsweilerMark A MenegusJohn D NearyLynn UhlJordan B StromChristopher B FordyceEmile FerrariJohanne SilvainFrances O WoodBenoit DaneaultTamar S PolonskyManohara SenaratneEtienne PuymiratClaire BouletiBenoit LattucaHarvey D WhiteSheryl F KelseyPhillippe Gabriel StegJohn H Alexandernull nullPublished in: The New England journal of medicine (2023)
In patients with acute myocardial infarction and anemia, a liberal transfusion strategy did not significantly reduce the risk of recurrent myocardial infarction or death at 30 days. However, potential harms of a restrictive transfusion strategy cannot be excluded. (Funded by the National Heart, Lung, and Blood Institute and others; MINT ClinicalTrials.gov number, NCT02981407.).
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