Corneal Cross-Linking With Riboflavin Using Sunlight.

Sunlight exposure of ex-vivo corneas soaked in both 0.1% and 0.5% riboflavin resulted in increased corneal stiffness. Specifically, 0.1% riboflavin with longer UV-A exposure showed a trend for a greater stiffening effect, which might open new alleys for the use of oral riboflavin and fractioned sunlight exposure as less invasive CXL techniques.