Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease.

Naga P ChalasaniR VuppalanchiM RinellaM S MiddletonM S SiddiquiA S BarrittO KoltermanO FloresC AlonsoM Iruarrizaga-LejarretaR Gil-RedondoC B SirlinMichael B Zemel

Published in: Alimentary pharmacology & therapeutics (2018)

These data support further evaluation of high-dose NS-0200 for treating NASH, especially in those with elevated ALT (NCT 02546609).

Keyphrases

clinical trial
double blind
high dose
dengue virus
open label
phase iii
placebo controlled
phase ii
study protocol
low dose
stem cell transplantation
electronic health record
pulmonary hypertension
pulmonary arterial hypertension
zika virus
big data
data analysis
aedes aegypti
machine learning