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Cell-type specific binocular interactions in mouse visual thalamus.

Sean P MastersonGovin GovindaiahWilliam GuidoMartha Elise Bickford
Published in: bioRxiv : the preprint server for biology (2024)
In vitro dual color optogenetics examined convergence of eye-specific retinal inputs to thalamocortical (relay) cells and interneurons in the dLGNThe majority of relay cells receive monocular excitatory retinogeniculate input while the majority of interneurons receive binocular inputBinocular relay cells are located in and around the ipsilateral patch whereas binocular interneurons are distributed throughout the dLGNThe majority of relay cells receive binocular retinogeniculate-evoked inhibitiondLGN interneurons are interconnected, receiving both monocular and binocular retinogeniculate-evoked inhibition.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • optical coherence tomography