Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers.
Carolina Perales-ChordaDavid ObesoLaura TwomeyAyelén Rojas-BenedictoLeonor Puchades-CarrascoMarta RocaAntonio Pineda-LucenaJose Julio LagunaCoral BarbasVanesa EstebanJaume Martí-GarridoEthel Ibañez-EchevarriaRamón López-SalgueiroDomingo BarberAlma VillaseñorDolores Hernández Fernández de RojasPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
The results of this exploratory study provide the first evidence that different anaphylactic triggers or severity induce differential metabolic changes along time or at specific time-point, respectively. Besides, the basal status T0 might identify high-risk patients, thus opening new ways to understand, diagnose and treat anaphylaxis.