Menstrual blood-derived mesenchymal stromal cells efficiently ameliorate experimental autoimmune encephalomyelitis by inhibiting T cell activation in mice.

Yonghai LiHaiyao GaoTobias M BrunnerXiaoxi HuYushan YanYanli LiuLiang QiaoPeihua WuMeng LiQing LiuFen YangJuntang LinMax LöhningPing Shen

Published in: Stem cell research & therapy (2022)

Our data demonstrate that the readily available MB-MSCs significantly reduced the disease severity of EAE upon transplantation. Thus, they have the potential to be developed as ready-to-use allo-MSCs in MS-related inflammation.

Keyphrases

mesenchymal stem cells
umbilical cord
bone marrow
oxidative stress
mass spectrometry
multiple sclerosis
ms ms
electronic health record
signaling pathway
cell therapy
high fat diet induced
big data
machine learning
skeletal muscle
wild type
drug induced