Opioids impair Nivolumab outcomes: a retrospective propensity score analysis in non-small-cell lung cancer.
Yoshihiko TaniguchiAkihiro TamiyaYoshinobu MatsudaYuichi AdachiTakatoshi EnomotoKouji AzumaShunichi KounoAkihiro TokoroShinji AtagiPublished in: BMJ supportive & palliative care (2020)
Patients with NSCLC receiving regular opioid administration at nivolumab treatment initiation had a worse nivolumab treatment outcome than patients without opioid use.
Keyphrases
- end stage renal disease
- chronic pain
- pain management
- newly diagnosed
- small cell lung cancer
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- metabolic syndrome
- patient reported outcomes
- combination therapy
- adipose tissue
- skeletal muscle
- insulin resistance
- epidermal growth factor receptor
- patient reported
- tyrosine kinase