Targeting the Glucocorticoid Receptor Reduces Binge-Like Drinking in High Drinking in the Dark (HDID-1) Mice.

Antonia M Savarese Angela R OzburnPamela MettenJason P SchlumbohmWyatt R HackKathryn LeMoineHazel HuntFelix HauschMichael BauderJohn C Crabbe

Published in: Alcoholism, clinical and experimental research (2020)

These data suggest that the selection process increased sensitivity to GR antagonism on EtOH intake in the HDID-1 mice, and support a role for the GR as a genetic risk factor for high-risk alcohol intake.

Keyphrases

alcohol consumption
high fat diet induced
weight gain
electronic health record
type diabetes
wild type
drug delivery